Ausgewählte Publikationen Prof. Dr. Reinhard Paschke
[1.] Weber, Lisa A., Meissner, Jessica, Delarocque, Julien, Kalbitz, Jutta, Feige, Karsten, Kietzmann, Manfred, Michaelis, Anne, Paschke, Reinhard, Michael, Julia, Pratscher, Barbara, and Cavalleri, Jessika M. V. Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro. BMC Vet.Res. 16[1], 44. 2020.
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[2.] Bache, Matthias, Hein, Anja, Petrenko, Marina, Guettler, Antje, Kessler, Jacqueline, Wichmann, Henri, Kappler, Matthias, Emmerich, Daniel, Paschke, Reinhard, and Vordermark, Dirk. Evaluation of the Betulinic Acid-Cisplatin conjugate APC and its precursor DE9B for the treatment of human malignant glioma. Chem.-Biol.Interact. 314, 108841. 2019.
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[3.] Vanchanagiri, Kranthi, Emmerich, Daniel, Bruschke, Monique, Bache, Matthias, Seifert, Franziska, Csuk, Rene, Vordermark, Dirk, and Paschke, Reinhard. Synthesis and biological investigation of new carbonic anhydrase IX (CAIX) inhibitors. Chem.-Biol.Interact. 284, 12-23. 2018.
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[4.] Kaluerovic, Goran N., Bulatovic, Mirna, Krajnovic, Tamara, Paschke, Reinhard, Zmejkovski, Bojana B., Maksimovic-Ivanic, Danijela, and Mijatovic, Sanja. (18-crown-6)potassium(I) yrichlorido[28-acetyl-3- (tris-(hydroxylmethyl)amino-ethane)betulinic ester-κN]platinum(II): synthesis and in vitro antitumor activity. Inorganics 5[3], 56-1-56/13. 2017.
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[5.] Liebscher, G., Vanchangiri, K., Mueller, Th, Feige, K., Cavalleri, J.-M. V., and Paschke, R. In vitro anticancer activity of Betulinic acid and derivatives thereof on equine melanoma cell lines from grey horses and invivo safety assessment of the compound NVX-207 in two horses. Chem.-Biol.Interact. 246, 20-29. 2016.
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[6.] Natalio, Filipe, Tahir, Muhammad Nawaz, Friedrich, Norman, Koeck, Margret, Fritz-Popovski, Gerhard, Paris, Oskar, and Paschke, Reinhard. Structural analysis of Gossypium hirsutum fibers grown under greenhouse and hydroponic conditions. J.Struct.Biol. 194[3], 292-302. 2016.
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[7.] Bache, Matthias, Muench, Christin, Guettler, Antje, Wichmann, Henri, Theuerkorn, Katharina, Emmerich, Daniel, Paschke, Reinhard, and Vordermark, Dirk. Betulinyl sulfamates as anticancer agents and radiosensitizers in human breast cancer cells. Int.J.Mol.Sci. 16[11], 26249-26262. 2015.
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[8.] Bache, Matthias, Bernhardt, Stephan, Passin, Sarina, Wichmann, Henri, Hein, Anja, Zschornak, Martin, Kappler, Matthias, Taubert, Helge, Paschke, Reinhard, and Vordermark, Dirk. Betulinic acid derivatives NVX-207 and B10 for treatment of glioblastoma-an in vitro study of cytotoxicity and radiosensitization. Int.J.Mol.Sci. 15[11], 19777-19790. 2014.
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[9.] Emmerich, Daniel, Vanchanagiri, Kranthi, Baratto, Leopoldo C., Schmidt, Harry, and Paschke, Reinhard. Synthesis and studies of anticancer properties of lupane-type triterpenoid derivatives containing a cisplatin fragment. Eur.J.Med.Chem. 75, 460-466. 2014.
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[10.] Fischer, Sebastian, Ronellenfitsch, Michael W., Thiepold, Anna Luisa, Harter, Patrick N., Reichert, Sebastian, Koegel, Donat, Paschke, Reinhard, Mittelbronn, Michel, Weller, Michael, Steinbach, Joachim P., Fulda, Simone, and Baehr, Oliver. Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid. PLoS One 9[4], e94921-1-e94921/10. 2014.
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[11.] Bache, Matthias, Bernhardt, Stephan, Hein, Anja, Passin, Sarina, Zschornak, Martin, Paschke, Reinhard, and Vordermark, Dirk. Betulinic acid derivatives for in vitro glioblastoma therapy. Exp.Strahlenther.Klin.Strahlenbiol. 22, 43-47. 2013.
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[12.] Baratto, Leopoldo C., Porsani, Mariana V., Pimentel, Ida C., Pereira Netto, Adaucto B., Paschke, Reinhard, and Oliveira, Bras H. Preparation of betulinic acid derivatives by chemical and biotransformation methods and determination of cytotoxicity against selected cancer cell lines. Eur.J.Med.Chem. 68, 121-131. 2013.
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[13.] Blazevski, Jana, Petkovic, Filip, Momcilovic, Miljana, Paschke, Reinhard, Kaluderovic, Goran N., Mostarica Stojkovic, Marija, and Miljkovic, Djordje. Betulinic acid regulates generation of neuroinflammatory mediators responsible for tissue destruction in multiple sclerosis in vitro. Acta Pharmacol.Sin. 34[3], 424-431. 2013.
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[14.] Chaudhuri, Sangeeta Roy, Kaludjerovic, Goran N., Bette, Martin, Schmidt, Juergen, Schmidt, Harry, Paschke, Reinhard, and Steinborn, Dirk. Synthesis, characterization and cytotoxicity studies of platinum(II) complexes with amino acid ligands in various coordination modes. Inorg.Chim.Acta 394, 472-480. 2013.
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[15.] Ludwig, Gerd, Kaluderovic, Goran N., Rueffer, Tobias, Bette, Martin, Korb, Marcus, Block, Michael, Paschke, Reinhard, Lang, Heinrich, and Steinborn, Dirk. Cationic arene ruthenium(II) complexes with chelating P-functionalized alkyl phenyl sulfide and sulfoxide ligands as potent anticancer agents. Dalton Trans. 42[11], 3771-3774. 2013.
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[16.] Ceballos-Torres, Jesus, Gomez-Ruiz, Santiago, Kaluderovic, Goran N., Fajardo, Mariano, Paschke, Reinhard, and Prashar, Sanjiv. Naphthyl-substituted titanocene dichloride complexes: Synthesis, characterization and in vitro studies. J.Organomet.Chem. 700, 188-193. 2012.
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[17.] Ceballos-Torres, Jesus, Caballero-Rodriguez, Maria J., Prashar, Sanjiv, Paschke, Reinhard, Steinborn, Dirk, Kaluderovic, Goran N., and Gomez-Ruiz, Santiago. Synthesis, characterization and in vitro biological studies of titanocene(IV) derivatives containing different carboxylato ligands. J.Organomet.Chem. 716, 201-207. 2012.
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[18.] Garcia-Penas, Alberto, Gomez-Ruiz, Santiago, Perez-Quintanilla, Damian, Paschke, Reinhard, Sierra, Isabel, Prashar, Sanjiv, del Hierro, Isabel, and Kaluderovic, Goran N. Study of the cytotoxicity and particle action in human cancer cells of titanocene-functionalized materials with potential application against tumors. J.Inorg.Biochem. 106[1], 100-110. 2012.
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[19.] Kaluderovic, Goran N., Gomez-Ruiz, Santiago, Maksimovic-Ivanic, Danijela, Paschke, Reinhard, and Mijatovic, Sanja. Metals in medicine. Bioinorg.Chem.Appl. 705907, 2. 2012.
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[20.] Kaluderovic, Goran N., Dietrich, Andrea, Kommera, Harish, Kuntsche, Judith, Maeder, Karsten, Mueller, Thomas, and Paschke, Reinhard. Liposomes as vehicles for water insoluble platinum-based potential drug: 2-(4-(Tetrahydro-2H-pyran-2-yloxy)-undecyl)-propane-1,3-diamminedichloroplatinum(II). Eur.J.Med.Chem. 54, 567-572. 2012.
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[21.] Ludwig, Gerd, Kaluderovic, Goran N., Bette, Martin, Block, Michael, Paschke, Reinhard, and Steinborn, Dirk. Highly active neutral ruthenium(II) arene complexes: Synthesis, characterization, and investigation of their anticancer properties. J.Inorg.Biochem. 113, 77-82. 2012.
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[22.] Molter, Anja, Kaluderovic, Goran N., Kommera, Harish, Paschke, Reinhard, Langer, Thorsten, Poettgen, Rainer, and Mohr, Fabian. Synthesis, structures, 119Sn Moessbauer spectroscopic studies and biological activity of some tin(IV) complexes containing pyridyl functionalised selenosemicarbazonato ligands. J.Organomet.Chem. 701, 80-86. 2012.
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[23.] Sanchez-Munoz, Sergio, Gomez-Ruiz, Santiago, Perez-Quintanilla, Damian, Morante-Zarcero, Sonia, Sierra, Isabel, Prashar, Sanjiv, Paschke, Reinhard, and Kaluderovic, Goran N. Preliminary Study of the Anticancer Applications of Mesoporous Materials Functionalized with the Natural Product Betulinic Acid. ChemMedChem 7[4], 670-679. 2012.
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[24.] Bache, Matthias, Zschornak, Martin P., Passin, Sarina, Kessler, Jacqueline, Wichmann, Henri, Kappler, Matthias, Paschke, Reinhard, Kaluderovic, Goran N., Kommera, Harish, Taubert, Helge, and Vordermark, Dirk. Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions. Radiat.Oncol. 6, 111. 2011.
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[25.] Biersack, Bernhard, Dietrich, Andrea, Zoldakova, Miroslava, Kalinowski, Bernd, Paschke, Reinhard, Schobert, Rainer, and Mueller, Thomas. Lipophilic Pt(II) complexes with selective efficacy against cisplatin-resistant testicular cancer cells. J.Inorg.Biochem. 105[12], 1630-1637. 2011.
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[26.] Gallego, Beatriz, Kaluderovic, Milena R., Kommera, Harish, Paschke, Reinhard, Hey-Hawkins, Evamarie, Remmerbach, Torsten W., Kaluderovic, Goran N., and Gomez-Ruiz, Santiago. Cytotoxicity, apoptosis and study of the DNA-binding properties of bi- and tetranuclear gallium(III) complexes with heterocyclic thiolato ligands. Invest.New Drugs 29[5], 932-944. 2011.
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[27.] Gomez-Ruiz, Santiago, Sanchez-Munoz, Sergio, Perez-Quintanilla, Damian, Morante-Zarcero, Sonia, Sierra, Isabel, Prashar, Sanjiv, Paschke, Reinhard, and Kaluerovi, Goran N. Functionalized nanostructured materials: In search of novel systems against bone tumors. Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011 , INOR-147. 2011.
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[28.] Kaluderovic, G. N. and Paschke, R. Anticancer metallotherapeutics in preclinical development. Curr.Med.Chem. 18[31], 4738-4752. 2011.
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[29.] Kaluderovic, Milena R., Kaluderovic, Goran N., Gomez-Ruiz, Santiago, Paschke, Reinhard, Hemprich, Alexander, Kuehling, Jan, and Remmerbach, Torsten W. Organogallium(III) complexes as apoptosis promoting anticancer agents for head and neck squamous cell carcinoma (HNSCC) cell lines. J.Inorg.Biochem. 105[2], 164-170. 2011.
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[30.] Kommera, Harish, Kaluderovic, Goran N., Kalbitz, Jutta, and Paschke, Reinhard. Lupane Triterpenoids-Betulin and Betulinic acid derivatives induce apoptosis in tumor cells. Invest.New Drugs 29[2], 266-272. 2011.
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[31.] Scholz, Matthias, Kaluderovic, Goran N., Kommera, Harish, Paschke, Reinhard, Will, Joanna, Sheldrick, William S., and Hey-Hawkins, Evamarie. Carbaboranes as pharmacophores: Similarities and differences between aspirin and asborin. Eur.J.Med.Chem. 46[4], 1131-1139. 2011.
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[32.] Yousef, Rushdi I., Bette, Martin, Kaluderovic, Goran N., Paschke, Reinhard, Yiran, Cui, Steinborn, Dirk, and Schmidt, Harry. Structure determination and investigation on cytotoxicity of potassium dichlorido(L-prolinato)platinate(II) versus chlorido(dimethyl sulfoxide)(L-prolinato)platinum(II) complex -In vitro antitumor deactivation by Cl-/DMSO ligand exchange. Polyhedron 30[12], 1990-1996. 2011.
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[33.] Csuk, Rene, Barthel, Alexander, Kluge, Ralph, Stroehl, Dieter, Kommera, Harish, and Paschke, Reinhard. Synthesis and biological evaluation of antitumour-active betulin derivatives. Bioorg.Med.Chem. 18[3], 1344-1355. 2010.
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[34.] Csuk, Rene, Barthel, Alexander, Schwarz, Stefan, Kommera, Harish, and Paschke, Reinhard. Synthesis and biological evaluation of antitumor-active γ-butyrolactone substituted betulin derivatives. Bioorg.Med.Chem. 18[7], 2549-2558. 2010.
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[35.] Gomez-Ruiz, Santiago, Prashar, Sanjiv, Walther, Till, Fajardo, Mariano, Steinborn, Dirk, Paschke, Reinhard, and Kaluderovic, Goran N. Cyclopentadienyltin(IV) derivatives: Synthesis, characterization and study of their cytotoxic activities. Polyhedron 29[1], 16-23. 2010.
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[36.] Kaluderovic, Goran N., Kommera, Harish, Hey-Hawkins, Evamarie, Paschke, Reinhard, and Gomez-Ruiz, Santiago. Synthesis and biological applications of ionic triphenyltin(IV) chloride carboxylate complexes with exceptionally high cytotoxicity. Metallomics 2[6], 419-428. 2010.
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[37.] Kaluderovic, Goran N., Paschke, Reinhard, Prashar, Sanjiv, and Gomez-Ruiz, Santiago. Synthesis, characterization and biological studies of 1-D polymeric triphenyltin(IV) carboxylates. J.Organomet.Chem. 695[15-16], 1883-1890. 2010.
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[38.] Kaluderovic, Goran N., Tayurskaya, Valentina, Paschke, Reinhard, Prashar, Sanjiv, Fajardo, Mariano, and Gomez-Ruiz, Santiago. Synthesis, characterization and biological studies of alkenyl-substituted titanocene(IV) carboxylate complexes. Appl.Organomet.Chem. 24[9], 656-662. 2010.
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[39.] Kaluderovic, M. R., Gomez-Ruiz, S., Paschke, R., Remmerbach, T. W., and Kaluderovic, G. N. Organogallium(III) complexes: a potential antitumor agents against the head and neck squamous cell carcinoma (HNSCC) cell lines. Phys.Chem.2010, Proc.Int.Conf.Fundam.Appl.Aspects Phys.Chem., 10th 2, 552-554. 2010.
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[40.] Kaluderovic, Milena R., Gomez-Ruiz, Santiago, Gallego, Beatriz, Hey-Hawkins, Evamarie, Paschke, Reinhard, and Kaluderovic, Goran N. Anticancer activity of dinuclear gallium(III) carboxylate complexes. Eur.J.Med.Chem. 45[2], 519-525. 2010.
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[41.] Kommera, Harish, Kaluderovic, Goran N., Bette, Martin, Kalbitz, Jutta, Fuchs, Petra, Fulda, Simone, Mier, Walter, and Paschke, Reinhard. In vitro anticancer studies of α- and β--glucopyranose betulin anomers. Chem.-Biol.Interact. 185[2], 128-136. 2010.
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[42.] Kommera, Harish, Kaluderovic, Goran N., Kalbitz, Jutta, Draeger, Birgit, and Paschke, Reinhard. Small structural changes of pentacyclic lupane type triterpenoid derivatives lead to significant differences in their anticancer properties. Eur.J.Med.Chem. 45[8], 3346-3353. 2010.
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[43.] Kommera, Harish, Kaluderovic, Goran N., Kalbitz, Jutta, and Paschke, Reinhard. Synthesis and Anticancer Activity of Novel Betulinic acid and Betulin Derivatives. Arch.Pharm.(Weinheim, Ger.) 343[8], 449-457. 2010.
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[44.] Kommera, Harish, Kaluderovic, Goran N., Dittrich, Sebastian, Kalbitz, Jutta, Draeger, Birgit, Mueller, Thomas, and Paschke, Reinhard. Carbamate derivatives of betulinic acid and betulin with selective cytotoxic activity. Bioorg.Med.Chem.Lett. 20[11], 3409-3412. 2010.
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[45.] Lazic, Jelena M., Vucicevic, Ljubica, Grguric-Sipka, Sanja, Janjetovic, Kristina, Kaluderovic, Goran N., Misirkic, Maja, Gruden-Pavlovic, Maja, Popadic, Dusan, Paschke, Reinhard, Trajkovic, Vladimir, and Sabo, Tibor J. Synthesis and in vitro Anticancer Activity of Octahedral Platinum(IV) Complexes with Cyclohexyl-Functionalized Ethylenediamine-N,N'-Diacetate-Type Ligands. ChemMedChem 5[6], 881-889. 2010.
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[46.] Paschke, R., Dietrich, A., Mueller, T., Kalinowski, B., and Kaluderovic, G. N. Novel platinum compound that overcomes cisplatin resistance and induces apoptosis. Phys.Chem.2010, Proc.Int.Conf.Fundam.Appl.Aspects Phys.Chem., 10th 2, 529-531. 2010.
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[47.] Vetter, Cornelia, Kaluderovic, Goran N., Paschke, Reinhard, Kluge, Ralph, Schmidt, Juergen, and Steinborn, Dirk. Synthesis, characterization and in vitro cytotoxicity studies of platinum(IV) complexes with thiouracil ligands. Inorg.Chim.Acta 363[11], 2452-2460. 2010.
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[48.] Gomez-Ruiz, Santiago, Gallego, Beatriz, Kaluderovic, Milena R., Kommera, Harish, Hey-Hawkins, Evamarie, Paschke, Reinhard, and Kaluderovic, Goran N. Novel gallium(III) complexes containing phthaloyl derivatives of neutral aminoacids with apoptotic activity in cancer cells. J.Organomet.Chem. 694[14], 2191-2197. 2009.
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[49.] Gomez-Ruiz, Santiago, Kaluderovic, Goran N., Polo-Ceron, Dorian, Tayurskaya, Valentina, Prashar, Sanjiv, Fajardo, Mariano, and Paschke, Reinhard. A novel alkenyl-substituted ansa-zirconocene complex with dual application as olefin polymerization catalyst and anticancer drug. J.Organomet.Chem. 694[18], 3032-3038. 2009.
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[50.] Kaluderovic, Goran N., Kommera, Harish, Schwieger, Sebastian, Paethanom, Anchan, Kunze, Michael, Schmidt, Harry, Paschke, Reinhard, and Steinborn, Dirk. Synthesis, characterization, in vitro antitumoral investigations and interaction with plasmid pBR322 DNA of R2eddp-platinum(IV) complexes (R = Et, n-Pr). Dalton Trans. [48], 10720-10726. 2009.
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[51.] Vetter, Cornelia, Wagner, Christoph, Kaluderovic, Goran N., Paschke, Reinhard, and Steinborn, Dirk. Synthesis, characterization, and cytotoxicity of trimethylplatinum(IV) complexes with 2-thiocytosine and 1-methyl-2-thiocytosine ligands. Inorg.Chim.Acta 362[1], 189-195. 2009.
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[52.] Vetter, Cornelia, Kaluderovic, Goran N., Paschke, Reinhard, Gomez-Ruiz, Santiago, and Steinborn, Dirk. Synthesis, structures and in vitro cytotoxicity studies of platinum(IV) complexes with N,S and S,S heterocyclic ligands. Polyhedron 28[17], 3699-3706. 2009.
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[53.] Willmann, M., Wacheck, V., Buckley, J., Nagy, K., Thalhammer, J., Paschke, R., Triche, T., Jansen, B., and Selzer, E. Characterization of NVX-207, a novel betulinic acid-derived anti-cancer compound. Eur.J.Clin.Invest. 39[5], 384-394. 2009.
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[54.] Zmejkovski, Bojana B., Kaluderovic, Goran N., Gomez-Ruiz, Santiago, Zizak, Zeljko, Steinborn, Dirk, Schmidt, Harry, Paschke, Reinhard, Juranic, Zorica D., and Sabo, Tibor J. Palladium(II) complexes with R2edda-derived ligands. Part II. Synthesis, characterization and in vitro antitumoral studies of R2eddip esters and palladium(II) complexes. Eur.J.Med.Chem. 44[9], 3452-3458. 2009.
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[55.] Dietrich, Andrea, Mueller, Thomas, Paschke, Reinhard, Kalinowski, Bernd, Behlendorf, Timo, Reipsch, Franziska, Fruehauf, Angelika, Schmoll, Hans Joachim, Kloft, Charlotte, and Voigt, Wieland. 2-(4-(tetrahydro-2H-pyran-2-yloxy)-undecyl)-propane-1,3-diamminedichloroplatinum(II): A Novel Platinum Compound that Overcomes Cisplatin Resistance and Induces Apoptosis by Mechanisms Different from that of Cisplatin. J.Med.Chem. 51[17], 5413-5422. 2008.
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[56.] Kaluderovic, Goran N., Schmidt, Harry, Schwieger, Sebastian, Wagner, Christoph, Paschke, Reinhard, Dietrich, Andrea, Mueller, Thomas, and Steinborn, Dirk. Platinum(IV) complexes with ethylenediamine-N,N'-diacetate diester (R2edda) ligands: Synthesis, characterization and in vitro antitumoral activity. Inorg.Chim.Acta 361[5], 1395-1404. 2008.
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[57.] Kelly, Mairead E., Dietrich, Andrea, Gomez-Ruiz, Santiago, Kalinowski, Bernd, Kaluderovic, Goran N., Mueller, Thomas, Paschke, Reinhard, Schmidt, Juergen, Steinborn, Dirk, Wagner, Christoph, and Schmidt, Harry. Platinum(IV) Metallacrown Ethers: Synthesis, Structures, Host Properties and Anticancer Evaluation. Organometallics 27[19], 4917-4927. 2008.
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[58.] Lindner, Ronald, Kaluderovic, Goran N., Paschke, Reinhard, Wagner, Christoph, and Steinborn, Dirk. Synthesis and characterization of dinuclear pyrazolato bridged platinum(IV) complexes. Polyhedron 27[3], 914-922. 2008.
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[59.] Kaluderovic, Goran N., Schmidt, Harry, Paschke, Reinhard, Kalinowski, Bernd, Dietrich, Andrea, Mueller, Thomas, and Steinborn, Dirk. Platinum(II) complexes with L-methionylglycine and L-methionyl-L-leucine ligands: Synthesis, characterization and in vitro antitumoral activity. J.Inorg.Biochem. 101[3], 543-549. 2007.
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[60.] Schobert, Rainer, Biersack, Bernhard, Dietrich, Andrea, Grotemeier, Antje, Mueller, Thomas, Kalinowski, Bernd, Knauer, Sebastian, Voigt, Wieland, and Paschke, Reinhard. Monoterpenes as Drug Shuttles: Cytotoxic (6-Aminomethylnicotinate)dichloridoplatinum(II) Complexes with Potential To Overcome Cisplatin Resistance. J.Med.Chem. 50[6], 1288-1293. 2007.
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[61.] Brock, Andrea, Herzfeld, Tobias, Paschke, Reinhard, Koch, Marcus, and Draeger, Birgit. Brassicaceae contain nortropane alkaloids. Phytochemistry (Elsevier) 67[18], 2050-2057. 2006.
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[62.] Paschke, Reinhard. Employment of metal complexes as functional units for the synthesis of new compounds with liquid crystalline or cytotoxic characteristics. No. 2004.
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[63.] Paschke, Reinhard, Liebsch, Stefan, Tschierske, Carsten, Oakley, Michael A., and Sinn, Ekkehard. Synthesis and Mesogenic Properties of Binuclear Copper(II) Complexes Derived from Salicylaldimine Schiff Bases. Inorg.Chem. 42[25], 8230-8240. 2003.
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[64.] Paschke, Reinhard, Kalbitz, Jutta, Paetz, Christian, Luckner, Martin, Mueller, Thomas, Schmoll, Hans Joachim, Mueller, Helmut, Sorkau, Eduard, and Sinn, Ekkehard. Cholic acid-carboplatin compounds (CarboChAPt) as models for specific drug delivery: synthesis of novel carboplatin analogous derivatives and comparison of the cytotoxic properties with corresponding cisplatin compounds. J.Inorg.Biochem. 94[4], 335-342. 2003.
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[65.] Paschke, Reinhard, Paetz, Christian, Mueller, Thomas, Schmoll, Hans Joachim, Mueller, Helmut, Sorkau, Eduard, and Sinn, Ekkehard. Biomolecules linked to transition metal complexes - new chances for chemotherapy. Curr.Med.Chem. 10[19], 2033-2044. 2003.
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[66.] Afrasiabi, Zahra, Muller, Helmut, Muller, Thomas, Paschke, Reinhard, Paetz, Christian, Sinn, Ekkehard, and Sorkau, Edward. Modified platinum drugs. Various carriers for drug transmission and targeting. Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002 , MEDI-071. 2002.
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[67.] Liebsch, Stephan, Oakley, Michael, Paschke, Reinhard, and Sinn, Ekkehard. New principles in metallomesogen structure-magnetism correlations. Inorg.Chem.Commun. 5[7], 525-526. 2002.
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[68.] Paschke, Reinhard, Balkow, Doerte, and Sinn, E. Lowering Melting Points in Asymmetrically Substituted Salen-Copper(II) Complexes Exhibiting Mesomorphic Behavior. Structure of the Mesogen Cu(5-hexyloxySalen). Inorg.Chem. 41[7], 1949-1953. 2002.
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[69.] Paschke, Reinhard, Muller, Thomas, Paetz, Christian, Simon, Heike, Schmoll, Hans Joachim, and Sinn, Ekkehard. Highly effective cytotoxic drugs. Synthesis and activities of a variety of spacer-linked bile acid CisPlatin and CarboPlatin derivatives. Abstracts of Papers, 223rd ACS National Meeting, Orlando, FL, United States, April 7-11, 2002 , MEDI-140. 2002.
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[70.] Paschke, R., Kalbitz, J., and Paetz, C. Novel spacer linked bile acid-cisplatin compounds as a model for specific drug delivery, synthesis and characterization. Inorg.Chim.Acta 304[2], 241-249. 2000.
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[71.] Kalbitz, Jutta, Paschke, Reinhard, and Sinn, Ekkehard. New prespectives on drug design: Platinum antitumor complexes. Book of Abstracts, 214th ACS National Meeting, Las Vegas, NV, September 7-11 , INOR-375. 1997.
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[72.] Budig, Hansjoerg, Lunkwitz, Ralph, Paschke, Reinhard, Tschierske, Carsten, Nuetz, Ulrich, Diele, Siegmar, and Pelzl, Gerhard. The influence of heteroatoms and branchings on the liquid-crystalline properties of cyclotriveratrylene derivatives. J.Mater.Chem. 6[8], 1283-1289. 1996.
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[73.] Budig, Hansjoerg, Diele, Siegmar, Paschke, Reinhard, Stroehl, Dieter, and Tschierske, Carsten. Mesomorphic properties and monolayer behavior of novel liquid crystalline exo-calix[4]arene derivatives. J.Chem.Soc., Perkin Trans.2 [9], 1901-1906. 1996.
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[74.] Blake, Antony B., Chipperfield, John R., Hussain, Wasif, Paschke, Reinhard, and Sinn, Ekkehard. Effects of Ligand Substituents (F for H; OR for R) on Mesogenic Properties of M(Salen) Derivatives (M = Cu, Ni, VO). New Fluoro-Substituted Complexes and Crystal Structure of the Mesogen Ni(5-hexylSalen). Inorg.Chem. 34[5], 1125-1129. 1995.
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[75.] Budig, Hansjoerg, Diele, Siegmar, Goering, Petra, Paschke, Reinhard, Sauer, Christiane, and Tschierske, Carsten. Synthesis and investigations of new liquid-crystalline compounds by combination of the pyramidic tribenzocyclononene unit and calamitic structural units. J.Chem.Soc., Perkin Trans.2 [4], 767-775. 1995.
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[76.] Budig, Hansjoerg, Diele, Siegmar, Goering, Petra, Paschke, Reinhard, Sauer, Christiane, and Tschierske, Carsten. New liquid crystalline materials by combination of pyramidic and calamitic structural units. J.Chem.Soc., Chem.Commun. [20], 2359-2360. 1994.
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[77.] Kresse, H., Szulzewsky, I., Diele, S., and Paschke, R. Stabilization and induction of liquid crystalline phases by hydrogen bonds. Mol.Cryst.Liq.Cryst.Sci.Technol., Sect.A 238, 13-19. 1994.
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[78.] Paschke, R., Balkow, D., Letko, I., and Pelzl, G. Di[2-(4-substituted-phenyl)-3-mercapto-propenato]nickel(II) complexes. Metallo-mesogens exhibiting broad nematic ranges. Liq.Cryst. 16[6], 1105-1107. 1994.
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[79.] Budig, H., Paschke, R., Diele, S., Letko, I., and Pelzl, G. Bowl-shaped liquid crystals - new derivatives of cyclotriveratrylene and calix[4]arene. Ber.Bunsen-Ges.Phys.Chem. 97[10], 1355-1357. 1993.
Ref Type: Journal (Full)
[80.] Heinemann, Susanne, Paschke, Reinhard, and Kresse, Horst. Competition between dipolar and steric interactions in swallow-tailed compounds. Liq.Cryst. 13[3], 373-380. 1993.
Ref Type: Journal (Full)
[81.] Kresse, Horst, Heinemann, Susanne, Paschke, Reinhard, and Weissflog, Wolfgang. Organization and disorganization of short range structures in swallow-tailed liquid crystals. Ber.Bunsen-Ges.Phys.Chem. 97[10], 1337-1342. 1993.
Ref Type: Journal (Full)
[82.] Kresse, Horst, Dorscheid, Claudia, Szulzewski, Ilka, Frank, Robert, and Paschke, Reinhard. Stabilization and destabilization of thermotropic liquid crystalline phases by hydrogen bondings. Ber.Bunsen-Ges.Phys.Chem. 97[10], 1345-1349. 1993.
Ref Type: Journal (Full)
[83.] Paschke, Reinhard, Rosenfeld, Uli, and Zaschke, Horst. The influence of heteroaromatic rings on mesomorphic properties. I. A new series of pyridazine- and pyridine-carboxylates. Liq.Cryst. 11[1], 145-150. 1992.
Ref Type: Journal (Full)
[84.] Paschke, R., Balkow, D., Baumeister, U., Hartung, H., Chipperfield, J. R., Blake, A. B., Nelson, P. G., and Gray, G. W. Di(5-substituted-salicylidene)ethylenediaminato complexes. Part II. Mesomorphic properties of di(5-alkylsalicylidene)ethylenediaminato nickel(II) and copper(II) complexes and an x-ray structure determination of [di(5-hexyloxy salicylidene)ethylenediaminato]nickel(II). Mol.Cryst.Liq.Cryst. 188, 105-118. 1990.
Ref Type: Journal (Full)
[85.] Paschke, R., Zaschke, H., Hauser, A., and Demus, D. Synthesis and liquid-crystalline properties of compounds incorporating the 2,6,7-trioxabicyclo(2.2.2)octane. Liq.Cryst. 6[4], 397-407. 1989.
Ref Type: Journal (Full)
[86.] Paschke, R., Zaschke, H., Maedicke, A., Chipperfield, J. R., Blake, A. B., Nelson, P. G., and Gray, G. W. Liquid crystalline transition metal complexes derived from di(5-alkyloxysalicylidene)ethylenediamines. Mol.Cryst.Liq.Cryst., Lett.Sect. 6[3], 81-85. 1988.
Ref Type: Journal (Full)
[87.] Paschke, Reinhard, Staehler, Katrin, and Zaschke, Horst. Synthesis of new glyoxylates. Z.Chem. 28[9], 333. 1988.
Ref Type: Journal (Full)
[88.] Paschke, Reinhard and Zaschke, Horst. New liquid crystal esters of 5-n-butyl-pyridine-2-carboxylic acid. Z.Chem. 26[2], 64-65. 1986.
Ref Type: Journal (Full)
[89.] De Liveira, Bras Heleno, Barato, Leopoldo Clemente, and Paschke, Reinhard. Antitumoral substances derived from betulinic acid and its production method. (Universidade Federal do Parana, Brazil. 2015-102015018628[102015018628], 17pp. BR. 4-8-2015.
Ref Type: Patent
[90.] Demus, Dietrich, Zaschke, Horst, Hauser, Anton, and Paschke, Reinhard. Preparation of 2,6,7-trioxabicyclo[2.2.2]octane derivative liquid crystals. (Martin-Luther-Universitaet Halle-Wittenberg, Ger. Dem. Rep. 1986-289181[248122], 7. DD. 16-4-1986.
Ref Type: Patent
[91.] Demus, Dietrich, Zaschke, Horst, Paschke, Reinhard, and Hauser, Anton. Nematic liquid-crystal compositions containing 1,4-substituted 2,6,7-trioxabicyclo[2.2.2]octanes for optoelectronic devices. (Martin-Luther-Universitaet Halle-Wittenberg, Ger. Dem. Rep. 1986-289180[248136], 4. DD. 16-4-1986.
Ref Type: Patent
[92.] Demus, Dietrich, Zaschke, Horst, Paschke, Reinhard, and Wiegeleben, Adalbert. Liquid crystalline substances. (VEB Werk fuer Fernsehelektronik, Ger. Dem. Rep. and VEB Kombinat Mikroelektronik). 1985-3510735[3510735], 8. DE. 25-3-1985.
Ref Type: Patent
[93.] Kernert, Norbert, Schloesser, Klaus, Fleig, Wolfgang, Lesske, Joachim, Luckner, Martin, Brandsch, Matthias, Hause, Gerd, Paschke, Reinhard, Arnold, Manfred, and Frank, Willy. Mixture containing rare earths and polymers for prosthetics. (Forschungszentrum Karlsruhe G.m.b.H., Germany. 2000-EP10884[2001034196], 22. WO. 4-11-2000.
Ref Type: Patent
[94.] Mohr, Kristina, Koehler, Saskia, Zaschke, Horst, Wissflog, Wolfgang, Paschke, Reinhard, Kampa, Barbara, Scherf, Klaus Dieter, Schaefer, Wolfgang, Rosenfeld, Ulrich, and et al. Ferroelectric liquid crystals for display devices. (Martin-Luther-Universitaet Halle-Wittenberg, Ger. Dem. Rep. 1987-300041[257638], 9. DD. 19-2-1987.
Ref Type: Patent
[95.] Otto, Claus, Tucek, Eberhard, Barnikol-Oettler, Kurt, Weissflog, Wolfgang, Demus, Dietrich, Schmidt, Renate, and Paschke, Reinhard. Cholesteric liquid crystals containing mixtures of cholesteryl and β-sitosteryl esters for thermography. (Martin-Luther-Universitaet Halle-Wittenberg, Ger. Dem. Rep. 1986-294508[252884], 4. DD. 18-9-1986.
Ref Type: Patent
[96.] Paschke, Reinhard, Kalbitz, Jutta, and Paetz, Christian. Preparation of multifunctional spacers for the transportation of conjugates of physiologically active compounds. (Martin-Luther-Universitaet Halle-Wittenberg, Germany. 1999-19950686[19950686], 6. DE. 21-10-1999.
Ref Type: Patent
[97.] Paschke, Reinhard, Rosenfeld, Ulrich, Zaschke, Horst, Demus, Dietrich, Kresse, Horst, and Linstroem, Brita. Liquid-crystal mixtures with smectic C phases. (Martin-Luther-Universitaet Halle-Wittenberg, Germany. 1989-330843[286176], 4. DD. 17-7-1989.
Ref Type: Patent
[98.] Paschke, Reinhard, Voigt, Wieland, Mueller, Thomas, Kalbitz, Jutta, Maeder, Karsten, and Dietrich, Andrea. Platinum (II) compounds from 2-substituted propane-1,3-diamines for use as antitumor chemotherapeutic drugs. (Martin-Luther-Universitaet Halle-Wittenberg, Germany. 2005-102005047308[102005047308], 9pp. DE. 30-9-2005.
Ref Type: Patent
[99.] Paschke, Reinhard, Zaschke, Horst, Tschierske, Carsten, Kresse, Horst, and Demus, Dietrich. Liquid crystal composition having extended smectic C phase range and negative dielectric anisotropy. (Martin-Luther-Universitaet Halle-Wittenberg, Ger. Dem. Rep. 1989-329610[285104], 4. DD. 15-6-1989.
Ref Type: Patent
[100.] Selzer, Edgar, Jansen, Burkhard, and Paschke, Reinhard. Preparation of betulinic acid derivatives as medicaments for inhibiting tumor growth. (Austria). 2004-AT45[2004072092], 22. WO. 11-2-2004.
Ref Type: Patent
[101.] Zaschke, Horst. Liquid crystal composition having extended smectic C phase range. (Martin-Luther-Universitaet Halle-Wittenberg, Ger. Dem. Rep. 1989-329611[285105], 7. DD. 15-6-1989.
Ref Type: Patent